While we know all about esters, doctors think “lmao just give a 3 day half life every 14 days bro” which is why people like this end up screwed.
The worst is psych meds. They put people on monthly injections for anti-psychotics despite the fact that they clearly don’t last a month. Those patients then end up going insane for the last week of every month putting everyone at risk. Two week injections would solve it, but no. Monthly.
Medicine as a field just doesn’t seem to realise how much of a difference dosing interval makes. Whereas recreational users know because daily vs weekly is ridiculous obvious through side effects.
https://www.researchgate.net/figure/Multiple-dose-pharmacoki...