If you buy all components from Frame.work, yes. Nobody else to my knowledge is making compatible components for their laptops though, so we're still a ways away from having an ecosystem of options like desktop PCs have.

If you're not an EE, the only things you can buy 3rd party are RAM, SSD, and Wi-Fi modules. Which you can do the same for Thinkpads.

That said -- I do appreciate that partial upgrades are possible with Frame.work. I own one and when I upgrade the motherboard, even though I can only buy a motherboard upgrade from them, I won't be upgrading the case, display, and other things that don't need upgrades.