My guess is it would be possible to get Asahi Linux to interface with a card, but it would likely run into similar quirks that we hit on other Arm platforms (like AMD driver issues with cache coherence on Ampere).
Disclaimer: completely unaware of what that means.
Does it preclude such a card working _at all_ or can it still be used e.g for e.g CUDA?
Would it be possible for e.g Nvidia to create a special batch of cards or design that would work for such cases? (priced through the roof given the small user base but that'd also be the kind of user base who would drop stupid amounts of money without batting an eye)