Well part of the issue is that there are a lot of RCs (Research Chemicals) that dealers often try to pass off as LSD, but are really slight tweaks on the chemical. They tend to be much easier and cheaper to make, so the street market is flooded with them (25i-NBOME is quite prolific). This can be a bit dangerous as there have been some (admittedly anecdotal) horror stories with people using these.

As for real LSD, it's insanely potent, and even a single batch can yield thousands, hundreds of thousands of doses. So you could probably stay pretty mobile while producing large amounts, assuming access to proper ingredients and equipment. See above our fellow polyglot genius who was hauling ass all over the country and supplying most of Rock and Roll with it.

No sane person would discuss such matters, right?