It depends on the application. BBBs come in industrial variants (the Pis don't, so good luck using them in certain contexts), and have more UARTs, i2c and SPI buses, not to mention the PRUs...
That said, I've seen some neat shoestring-budget prototype projects done on BB hardware, so there's some market there. But it seems like their stuff is a bit expensive for low-end learners and hobbyists and missing some of the niceties you get if you convince your boss to buy a ComExpress-based industrial module, or (if you really twist their arm) something like the Arnouse BioDigital SBCs.