Ergonomic mice are what’s useless. They give your wrist the tilt it (may) need but the real panacea is to keep your wrist/forearm off the table by resting your elbow on your armrest and having your desk height match your armrest height.
I haven't actually even used it in years (lost during an office move), but now I instinctively use a regular mouse with my hand at least at a 45 degree angle to the table, instead of parallel with it, and I still have no strain. I think I'd have trouble doing that with a bog standard low profile office mouse, but my old Logitech mouse is chunky enough that it works for me without thinking about it.
My elbow was always on the armrest, but it was only after using a vertical mouse that I trained myself to not strain myself.