There may well be a better alternative to the local maximum of powerpoint and keynote out there somewhere, but Prezi sure isn't it. At first it was a novelty; now it's just annoying.
I missed a local Android developer group's meeting a month or two and I wanted to go back to review the materials from talk I missed. They mailed out a link to their presentation, which turned out to be a Prezi slideshow. I tried to find some of their code examples and gave up because trying to navigate the presentation wasn't worth my time.