Yes. All JS turned off by default unless it's on a whitelist. Takes a few days to get the whitelist set up, but its fairly straightforward.
Between this and uBlock, it makes the web a lot safer and resource intensive to browse. For example, people frequently cite Chrome as being faster than Firefox, but with my setup that has rarely been a the case in a very long time.
I've also generally found a strong correlation between websites that don't work or work badly without JS and them being websites I don't want to frequent. And when the website doesn't work without enabling most of the JS, including all the ad and tracking stuff? That's a good sign that I probably should never whitelist that website.
There's also just the matter of principle. If a website works just fine for my needs with most or all of the JS turned off, it wasn't really necessary in the first place was it?