you can use a mozilla.com user id to talk to someone with a matrix.org user id, or a kde.org user id
all servers are equal participants in rooms, so a room doesn't live on a specific server aside from servers being able to create friendly names pointing to them, but nothing stops #foo:kde.org from pointing to the exact same room as #bar:mozilla.org -- both servers are participating equally and have their own shortcut name to the room