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There’s Objective-S https://objective.st/Language

There's Pharo, which I understand to be a spiritual successor.

https://mooc.pharo.org/

The original Dart language designers gave Dart Smalltalk semantics with JavaScript syntax. But Dart’s users rebelled and forced Dart to adopt a more compile-time-type-checked type system.

Some of the original Dart designers have developed a new language Toit that is Smalltalk-like: https://toit.io/company/about

And previously Resilient Smalltalk.

https://news.ycombinator.com/item?id=27353255