Most power is generated in a centralized way anyways because it's much more efficient that way. The 'dregs' aren't connected because putting up the wire costs far more than the extra power yields. A few percentage points more efficient won't change the economics, especially if the wire is (a) lead and (b) dramatically more expensive.
3.5% per 1000km is respectfully, basically nothing. You'd get 85% of the power out of a line from SF to NY.
I'm not saying there aren't use cases for room temperature superconductors, I'm saying this is not one that's going to be top of the list.