This is a good example of the lack of epistemic humility OP was taking about.
At the risk of stating the obvious: we need to measure every weird idea we try, and do our best to isolate the variables. Easier said than done. But we broke it, it's our problem now.
Talking about humility: an excess of humility leads to fatalism. Some is good, but not too much if you want anything to happen. We're talking about fixing the ecosystem of a planet, of course it's ambitious.