Odds are you will definitely lose that personal connection as you go from working for "the owner" to working for a manager that reports to a VP that reports to the CEO that reports to the Board that reports to the shareholders.
But what I've seen in a lot of these "leaving" posts isn't quite that... It's more of a "the king has no clothes" epiphany: They go to work at a place thinking it's a thing-in-itself then wake up one day and realize how the sausage is being made.
So GOOG isn't a post-grad research lab: It's a company that sells ads. So GS isn't the equivalent of a fee only financial planner.
They never were more than that.. only the people involved thought they were something more.