Scientific and Technological Breakthroughs Created a New Kind of Fiction
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[^1] Like, published in the last twenty years or so.
Greg Bear had some interesting novels around retroviruses in the 90s, Darwin's Radio, and I've read some solarpunk stories that went into the right direction. Peter Watts has a PhD in Zoology which is maybe why Blindsight is so good.
Both are dramatically better writers than the vast majority of sci-fi authors I come across these days.
The Machine Stops (1909,1928)
A rare sci-fi story from E. M. Forster, more famous for period dramas - A Room with a View, A Passage to India, Howard's End.