It might've affected me negatively when I was younger or a teen, but now that I'm grown up, it just seems so... Stupid? Thinking back, I feel stupid for ever letting such unsophisticated attempts of a primitive world view ever even remotely affect me.
These day, at worst if they're irritating I just mute them. At best, it's an invitation for free trolling (making jokes about their dad on Grindr, telling them their dirty talk is giving me a distracting boner or "flirting" with them, saying they sound like a used-up twice-divorced wife, etc; it's easy to push these people's buttons).
Them throwing my game is much more annoying than them projecting their insecurities in voice chat, and sometimes it's hard to counter a disruptive player (sometimes you can work around them, but the game is much more challenging for the wrong reason).