From my viewpoint (in europe though) I only started hearing/seeing it during coronavirus.
Reactionary people weaponized vaccines with Gardasil - good Christian boys and girls are chaste until marriage, so vaccination is unnecessary. Sinners get gods punishment.
Crazy left-wing people cling to the autism rumors about vaccination.
All of this is magnified by politics and propaganda. Certain religious sects punch above their weight because of political factors - you can usually correlate this with measles outbreaks. Foreign influence operations encourage and stoke this stuff to encourage general unrest as well.