Singing synthesis as a new musical instrument (2012)
ieeexplore.ieee.org
ieeexplore.ieee.org
Articulatory synthesis creates a physical model of the vocal tract (usually by treating it as a tube of varying diameter).
Formant synthesis simulates peaks in the spectral signature (i.e. formants) by directly constructing bandpass filters with the appropriate center frequency and bandwidth.
https://en.wikipedia.org/wiki/Talk_box
In 1939, Alvino Rey, amateur radio operator W6UK, used a carbon throat microphone wired in such a way as to modulate his electric steel guitar sound. The mic, originally developed for military pilot communications, was placed on the throat of Rey's wife Luise King (one of The King Sisters), who stood behind a curtain and mouthed the words, along with the guitar lines. The novel-sounding combination was called "Singing Guitar", and employed on stage and in the movie Jam Session, as a "novelty" attraction, but was not developed further.
Singing synthesis is different, most notably through Vocaloid. It's like a piano roll for singing. With Vocaloid, you can use preset voices, input MIDI notes and words/lyrics, and actually synthesize the sung speech completely in the box, and with significantly more realism based on how the synthesizer has been specialized to do that exact task. It lets a songwriter who is not a singer to write songs with full vocals and instrumentals that they wouldn't be able to do otherwise, in the same way that a DAW/midi sequencer enables a different way of writing music that doesn't require it to ever be played to exist.
I found this video about a singing synthesis instrument also by Yamaha (as the author): https://www.youtube.com/watch?v=2hk-kOPdHAY
Most creative use of speech synthesis prior to this was limited to vocoders, which is really more speech transformation (requires speech input). The sound you hear from Kraftwerk, Daft Punk etc.
Though the VODER demonstrations are actually insanely impressive, especially for the time period.
https://en.wikipedia.org/wiki/Vocaloid
https://en.wikipedia.org/wiki/Hatsune_Miku
It's definitely a major part of internet history as well; even Nyan Cat is a small offshoot of the greater Vocaloid community. (The music, by DaniwellP was originally created using Hatsune Miku, covered with another synthesized voice, and later someone paired it up with the famous cat graphic.)
Edit: here's a sample of what someone skilled with Vocaloid can do. https://youtube.com/watch?v=KmvydnVTriE