Wasn't the origin of the small pox vaccine that people would rub the pustules from one person onto themselves?
Iirc, Edward Jenner's smallpox vaccine was based on cowpox, a related but less serious disease.
> This consisted of transferring to healthy people small amounts of material from smallpox sores, resulting in milder forms of illness and much lower mortality than natural infection. Some sources suggest practices of variolation were taking place as early as 200 BCE.
[1] https://www.who.int/news-room/spotlight/history-of-vaccinati...
It’s a bit disappointing your comment was disliked. It’s on topic and completely relevant.