There was a podcast with Joel and Jeff as they talked through the development of Stackoverflow. It seemed that Joel had hired Jeff to code it, and then discussed what it should be like, and then as Jeff had something to show they talked about where it would go.
Meanwhile, there is plenty of software physiology sprinkled all throughout. It was a fascinating podcast.
At least that's what I remember from it, I haven't listened to it since it came out, what... 15 years ago??