R-410A is being phased out in major markets including the US too over the next few years (R-22 has been banned for new equipment most places for more than a decade, and is banned entirely in the EU since 2015 for recharging existing units). My Mitsubishi air to air heat pumps (one from 2015 and one from 2018) were already R-32 (GWP 675, Ozone depletion potential 0) and my air to water (Sanden, installed 2022) is R-744 (which is CO2 - obviously GWP 1)