I haven't noticed any major issues. And, in fact, I have more issues with my Intel/nVidia laptop, especially with regards to power management.
https://gitlab.freedesktop.org/drm/amd/-/issues/2354
Additionally, fan, thermals, and battery life are all subpar on my 845 g9. The fan is not even exposed via hwmon. Thunderbolt/usb 4 is also a bit iffy. There's no display before the OS boots, which means I need to open the laptop for the disk encryption password. The laptop also gets stuck in weird low frequency states after suspend/resume randomly and unpredictably. The only saving grace for this elitebook is that the wifi is not soldered, so I can upgrade it down the line. Otherwise, Intel Thinkpads are better for almost everything else, including the keyboard. Tangentially related, the mesa-freeworld mess also only exists for AMD laptops. I don't fully understand the legal gymnastics behind why Intel is not affected, but the end user experience is terrible.
It's Zen3, however. I would assume the Framework 13 or 16 would function equally well and are Zen4-based.
Also the notebooks tested at phoronix.com are a good indicator to work (Lenovo Z13 for example). In the case of AMD a lot of work with suspend/resume just recently (August 2023) got patched, so generally with a recent Kernel you should be fine these days. https://www.phoronix.com/news/AMD-Linux-Fix-SR-Wakeups
I simply installed debian, and everything works perfect