Intracerebral hemorrhage among blood donors and their transfusion recipients | Hacker News Reader

Intracerebral hemorrhage among blood donors and their transfusion recipients

jamanetwork.com

54 pointsgeox12 comments

Looks like that's a prion disease, then.

Why would that be more likely an explanation than any other?

Contagious protein misfolding is what defines a prion disease.

Lots of things are contagious. What indicates to you this is a protein misfolding issue?

Because it is written In the article. The whole article is about the fact that the observed symptoms hint at cerebral amyloid angiopathy.

From Wikipedia:

Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the central nervous system and meninges.

Also Wikipedia:

Pathogenic amyloids form when previously healthy proteins lose their normal structure and physiological functions (misfolding) and form fibrous deposits within and around cells. These protein misfolding and deposition processes disrupt the healthy function of tissues and organs.

The submission URL currently points at

"Blood Transfusion and Brain Amyloidosis: Should We Be Worried?" https://jamanetwork.com/journals/jama/article-abstract/28094...

But, based on the submission title, I suspect this submission was intended to point at

"Intracerebral Hemorrhage Among Blood Donors and Their Transfusion Recipients" https://jamanetwork.com/journals/jama/article-abstract/28094...

Ok, we'll change to that from https://jamanetwork.com/journals/jama/article-abstract/28094.... Thanks!

Was the title edited? Because this comment does not seem relevant.

However I find coooffee's suggested JAMA article really interesting!

Yup, someone edited the title. Personally I found the other link more interesting.

Submitted URL was https://jamanetwork.com/journals/jama/article-abstract/28094.... Submitted title was "Risk of brain hemorrhage transmissible via blood transfusion"

Our software switched the URL because the original page contained this:

   <link rel="canonical" href="https://jamanetwork.com/journals/jama/fullarticle/2809443" />

... but that points to the same article. A mod edited the title, in keeping with the HN guidelines ("Please use the original title, unless it is misleading or linkbait; don't editorialize.")

I've switched the URL to ccooffee's suggestion now, and will edit the title accordingly.

Would be a shame if this happened to Peter Thiel or any of the other blood boy enthusiasts.

As much as you might dislike some people, wishing harm on others is kind of a dick move.

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