The exact same ethical issues and commercial in entices apply in 10 person teams and 2BN grants.
It looks to me like we need something like professional engineer status at any given organisation that has independent and legal personal sign off
(ie a railway engineer can simply stop for example the 10bn pound HS2 railway project by simply not signing off one piece of paper. And the management know that. And so they have to deal with him, whoever he is.
The CISO of even penn state has no such leverage.
Edit: I think we should look first to see what balance of powers exists in an organisation - labour represented by unions? Management vs tech? sales vs everyone else ?