This year something ate the leaves off all my cucumber plants and they stopped producing after about 3 weeks. In 6 or 7 years of having them, that has never happened before.
One year squirrels overran the neighborhood and did the same to tomatoes. (The little f-ers take one bite of a tomato and drop it. It's so frustrating.)
One year I had to go out of town unexpectedly for 2 weeks and we happened to have a dry few weeks. Most of my plants died or were in bad shape.
Just off the cuff, if I were planning to do this, I would personally immediately almost double the size of garden I was told I needed just because I expect there would be a lot of loss.