My internal filter is:

Sociology/Psych/Economics are almost all junk. Their conclusions may or may not be correct.

Medical studies are mostly junk. There's way too much financial incentive to show marginal improvement. Theraflu and anti-depressents come to mind. Both show a small effect in studies and launched billion dollar businesses.

Hard science stuff tends to be pretty good. Mostly just outright fraud and they usually end up getting caught.