Academically w.r.t maths, mathematicians start where computer scientists end. The biggest bane to graduation of a CompSci student is usually a basic combinatorics class. One guy I knew was given special dispensation to take the class after having exceeded the maximum number of fails allowed for a single class. He was to devote the entire term to just that class. He had finished everything else. Intro Biochem and Discrete Maths I were the two most failed classes.