This is very interesting, and I think massively underestimates the variability in how small molecular drugs are affected by the body. Small differences in molecules can have drastic effects on where, how, and how quickly they're adsorbed, and what systems they affect.

More than anything, I think this just underestimates the unpredictability of it all. To extend the author's metaphor, if you measure the 100 data points from shooting 10 different projectiles out of 10 different devices, on 10 different celestial bodies, you're still not going to have a lot of predictive power that can be generalized.