the humans live out their lives at 300°, absolute, using the kelvin scale. there's lots of interesting behavior in matter down to 4° or less, and some solids up past 4000°. going further, human science doesn't really have a good handle on what kinds of complex interactions can occur with alfvén waves and plasma currents; they don't even know what's going on with prominently (heh) observable phenomena on the surface of the sun or how to stabilize a tokamak. but to be conservative let's consider just the 4°–4000° temperature range where we have solids and liquids
from that temperature range, covering three orders of magnitude, carbon-chain molecules have interesting and complex behavior over the range 200°–500°, more or less. just a factor of 2.5. 13% of the temperature range. below 200° (-73°C) pretty much all organic chemicals crystallize and become brittle and nonliving, though there are a few boring exceptions like methane. above 500° (230°C) they are unstable, breaking apart into elemental carbon and methane, again with a very few exceptions like teflon. the temperature range over which carbon chains are practical to synthesize is smaller still
a chemist on titan (94° absolute) would consider implausible the suggestion that living cells could be made out of carbon-chain molecules dissolved in water, a material that doesn't even melt until hellish temperatures nearly three times the boiling point of methane. a chemist on venus (740° absolute) would consider implausible the suggestion that living cells could be made out of such absurdly unstable molecules as carbon-chain polymers — much less with amide groups, which she knows as violently reactive with ordinary everyday substances like red-hot sulfuric acid. moreover, she would consider the pressure on earth's surface (1% of atmospheric for a venusian) to be a good approximation to the vacuum of space, constantly exposed to sterilizing levels of ultraviolet from the sun
(venus and titan specifically are not covered in vegetation or presumably in chemists, but there are astronomical numbers of other planets with conditions like theirs, and as sagan's paper pointed out, antarctica isn't exactly a jungle either)
there are interesting things going on over the other 87% of the temperature range, too. at room temperature the humans mostly know phosphates as minerals that are unusually hard to melt, but phosphoric acid just starts to polymerize above about 500° absolute and stays liquid past 1000°, polymerizing more and more enthusiastically; some common phosphates remain solid past 2000°. neat silica becomes a useful solvent at temperatures a bit higher than that, and silicates of sodium or potassium can be liquid down to room temperature if plasticized with enough water; silica is nearly as abundant as carbon. ammonia is liquid from 195° to 240°, a narrower range than water (273° to 373°, which is a 3:4 ratio to ammonia's 4:5) but not ridiculously so, and shares many of water's interesting properties, and we already know many interesting substances that can be synthesized in an ammonia solution, including many that are not stable at room temperature (and therefore might be in a useful reactivity range in ammonia's liquid range). and there are 1.7 orders of magnitude of temperature below ammonia's freezing point before you get to liquid helium and the cosmic background radiation. most of the universe's volume is in that temperature range, though not most of its matter, and if dyson's 'future of life in an ever-expanding universe' is correct, those temperatures and below are where our descendants will spend the vast majority of history
but the humans really only know a tiny fraction of the possible complex molecules at those temperatures, because working with them in their laboratories is difficult, expensive, dangerous, and unprofitable; molecules that explode when you heat them up to room temperature, or solidify into refractory ceramics when cooled anywhere near it, will not yield useful drugs, elastomers, cheap injection-molding plastics, or fuels, so research into them has mostly been pure, not applied. the exceptions are mostly high-temperature ceramics research focused on finding the strongest and most refractory materials, not interesting synthesis pathways that can operate inside white-hot zirconia crucibles
but don't let the utterly disorderly behavior of, say, nitrogen chains at the melting point of water fool you into thinking their chemistry is trivial; most compounds that are stable at 10% of that temperature haven't been discovered yet
(by the humans)