I worked in the windows kernel team and my favorite story about DC is when he basically made x64 happen because he hated Itanium architecture so much. He worked with AMD and basically made it happen while cranking in his corner office.
I didn't think AMD64 was a good idea at the time because it was more of the same. But good on Dave for helping eliminate the cruft that pretty much killed the RISC revolution.
It has been used in GPUs though.
Presumably the resulting bad karma is why the Xbox never sold well in Japan.