One thing about CGA is that it was meant to be output via composite video instead of VGA-style RGBI. This video demonstrates the difference: https://youtu.be/niKblgZupOc?si=ASm2NFJx3I8Q9hTz
For example, here's a game (Kings Quest II) where they used the red, green, and brown palette with the background set to blue. A mode like that gave better options for color dithering since R G and B were all available, see here:
https://www.mobygames.com/game/123/kings-quest-ii-romancing-...