Cloudflare's control plane and analytics systems run primarily on servers in three data centers around Hillsboro, Oregon. The three data centers are independent of one another, each have multiple utility power feeds, and each have multiple redundant and independent network connections. The facilities were intentionally chosen to be at a distance apart that would minimize the chances that a natural disaster would cause all three to be impacted, while still close enough that they could all run active-active redundant data clusters.
If the three data centers are all around Hillsboro, Oregon, an earthquake could probably take out all three simultaneously.