I'd feel much better about it. Because I know that they'd have been killed in the front line by a shell - not in the Paris latrines by cholera.

My father's father fought in the Battle of the Bulge. They weren't pussies back then, you know.

How would you feel about your grandparents being used as a few more numbers to confirm that a drug is not, in fact, effective or safe in treating prostate cancer?

Typically when you're trying to "confirm" something it means you think you know it anyway. No, I don't think any p-value is worth dying for.

Your turn. Honest question: here's a story by a UK woman who jumped for joy to learn her cancer had spread, because it meant she could get into a trial:

http://www.telegraph.co.uk/health/9193018/Back-to-work-after...

How do you feel about this situation? Is it by any chance a little too "Tuskegee" for your sensitive ethical vibrissae?