When dealing with NUMA we know that cross-socket, or in this case cross-CCD, latencies are always higher than the ones within the same socket or same CCD. Usually multi-fold.
This article nicely lists the core-to-core latencies between the Intel and AMD microarchitectures: https://chipsandcheese.com/2023/07/17/genoa-x-server-v-cache...
So, if you're able to somehow take advantage of this knowledge in your code (e.g. by scheduling less latency-sensitive tasks to the other CCD), you may be able to improve your overall performance.
Edit: Though I'd still recommend heeding menaerus excellent sibling answer. Maybe not for this project, but it is great knowledge to have in your domain and I'd expect it to be relevant for the future.