Fascinating! It looks like PEP 723 (the one that was accepted provisionally) will allow you to embed a comment in your script that looks like this, to specify dependencies on request and rich:

  # /// pyproject
  # [run]
  # requires-python = ">=3.11"
  # dependencies = [
  #   "requests<3",
  #   "rich",
  # ]
  # ///
  
  import requests
  from rich.pretty import pprint
  
  resp = requests.get("https://peps.python.org/api/peps.json")
  data = resp.json()
  pprint([(k, v["title"]) for k, v in data.items()][:10])