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Comment by rogerkirkness | Hacker News Reader

The cognitive dissonance here is wild. Someone who has been 'writing about weight loss for decades' is celebrating the end of 'diet charlatans' because weight-loss drugs exist, but the drugs simply on GLP-1 to reduce how hungry people e- which is the same as dietary fibre does after you eat it.

We could eat fibre, but instead we take $1300/month injection drugs... so we don't have to eat fibre.

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No, dietary fiber is not the whole and complete solution to the problem.

If it was, then these drugs wouldn't exist.

If it was, then this problem wouldn't exist.

Please feel free to explain how increasing your dietary fiber intake can help solve this problem, but please also allow for other components to be a part of the overall solution.

Dietary fibre is a GLP-1 agonist, so if people ate enough fibre for the amount of calories they ate, no one except those with thyroid disorders would be overweight. This drug won't help with thyroid disorders. This drug will have long term side effects that are as bad as being overweight. Therefore, this drug should not be necessary, except that people won't eat enough fibre.

Honestly it’s not worth bothering with him. He’s fat and convinced it’s irreversible without medical intervention and is caused by his genetics. You can’t convince emotional thinkers with logic

And so, how much dietary fiber would you have to consume to equal the GLP-1 equivalent dose of the drugs referenced in the article?

It's being studied now, but generally speaking the benefits start to taper around 120g a day in existing studies we have about fibre. So it's most likely 'At least 120g/day and possibly more depending on what we learn studying GLP-1 further.

In contrast:

> The Metamucil powder dosage for adults and adolescents ages 12 and older is 3.4 grams (1 serving), mixed with 8 ounces of water, up to 3 times a day. The mixture should be consumed immediately after preparing it.

So, you're talking about 35.3 times the recommended Metamucil dose?

If a dose of Metamucil is a teaspoon, and a typical canister has 180 doses, you're talking about approximately one fifth of the entire container -- per day?

And drinking 282 ounces of water per day to wash down all that Metamucil?

That seems medically dangerous to me....

Welcome to the real world, where everything is backwards

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