I’m not sure I read the OP the same way you did. If you read it as “can I build a site on the scale of Reddit or Twitter with Drupal” then no, don’t build Reddit or Twitter with Drupal. If you read it as “will Drupal serve a site with user generated content” then yes, it will, but if you’re planning to be a top 10 site on the internet, you’ll need a custom stack.