The shortcut is different on macOS, hence your confusion. The combination is Cmd+Shift+R which is very close to where your fingers are in their resting state. On macOS you generally use Cmd everywhere where you would use Ctrl on Windows.
Thumb (cmd, near spacebar), pinkie (shift), index (r).
And this particular key combo is quite comfortable.
On every Mac I use, I go into Modifier Keys and switch CMD and CTRL. I started doing this when I first switched from windows to Mac about 20 years ago and have never switched back. It confuses other people when they use my computers, but it is what I'm accustomed to. I especially don't understand how people do CMD+X/C/V - the modifier key is just too close. Doing CTRL+X/C/V is so much more comfortable.
On Safari, it's actually Cmd+Alt+R (no Shift)
Which was very confusing for me as I couldn't solve a cache issue with the expected Cmd+Shift+R.
Oh, and Pinky on left Alt/Option, Thumb on left Cmd, Index on R. I've never learned to combine right and left modifiers :( Probably gaming has ruined me.
- left hand little finger on shift
- left hand thumb (??) on command
- left hand index finger on R