FDA shuts down enquiries about DNA contamination in Covid vaccines

brownstone.org

5 points·hammock··7 comments

until DNA sequences having features allowing cellular transfection [entry], and integration [inserting into host DNA] is found in vaccine, there is no basis for concern.

specific modification of a sequence of DNA is required for transfection, and integration. this is not a random occurance, and even best case outcome, is less than 10% success, and requires supportive conditions.

Perhaps you are right. It's an interesting area of research for sure, as the lipid nanoparticle (LNP) delivery system of these vaccines is new, and a lot of hypothesizing has been done that the residual DNA being encapsulated in the LNP makes it easier to transfect (the LNP is specifically designed to be able to enter cells) and resistant to the typical biological processes (nucleases) that would prevent integration

LNPs are actually better than that! they integrate with the cell membrane, and the mRNA moves through the cytoplasm.

so each cell that is ~transfected with mRNA has signature lipids in the membrane

Bullshit site. Bullshit article.

What does this even mean? Can someone eli5?

Someone altered the link to a paywalled version of the same article (for some reason). Here is the full article for free: https://brownstone.org/articles/fda-shuts-down-enquiries-abo...

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