I do not have evidence but there are lots of regulations, talking about Spain now, but also in Europe, that leave small players de-facto out by apparently good intentions and make big players almost monopolize markets. Banking system, energy are two examples in Spain but there are lots of small business that get smashed by the fact that by not being profitable enough, causing them economic damage makes them extinguish. Lots of small business have been shutting down in the last few years yet they keep increasing tax rates. Special mention to freelancers, the most mercilessly smashed group here, taking into account that you often cannot control what is coming in the next few months wealth-wise, since that is relatively irregular and self-sustained.
The system is built in harmful ways for most of us.