> Some programs are not well-suited for PySimpleGUI however. By definition, PySimpleGUI implements a subset of the underlying GUI frameworks' capabilities. It's difficult to define exactly which programs are well suited for PySimpleGUI and which are not. It depends on the details of your program. Duplicating Excel in every detail is an example of something not well suited for PySimpleGUI.
says absolutely nothing and gives the reader no useful leads as to the applicability of the framework to their project.
tl;dr: "you will be disappointed if you want to do something fancy"
(of course, should you want all three of (a) easy, (b) fancy, and (c) someone else has already done much of it for you, I'd bet you would be bound for disappointment anyway)