I sometimes find GUIs equivalent to comfort-food as you can just stroll through a gui interface without lot of cognitive overload that may come from a rarely used CLI.

A bit tangential to current discussion, but i came across CUDATEXT editor a few months ago here which provides a single file python API to let me use arbitrary GUI elements like MENU, INPUTS etc which editor is itself using. I currently generate my blog from editor itself with configuration done through these simple GUI elements.