For me, these class notes are the most thought-provoking stuff that has surfaced HN for a while. The first few lectures took this bird-eye view to entrepreneurship, which was very refreshing. Thiel's view about competition vs monopolies, or as he puts it, globalization vs technology, was a new point of view to me. And this more practical discussion about company culture is quite spot on in my experience: argumentative culture is better than too nice culture.