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Are there any commonly-used units more nonisotropic than the acre-foot? (its "unit cube" is 1 furlong x 1 chain x 1 foot)

Hmm, water related, there is the "Miner's Inch"

for which the "unit cube"(block?) would be like 1" x 1" x ~2300 miles by my (fast, bad) calculations.

Hubble's constant is typically measured in kilometers per second per megaparsec, which can be converted to Hertz.