If you are confused (like me) that this was about PyPI (Python packages repository) then no. It is about a project called PyPy (one can argue it is bad name) that is an implementation of python interpreter but without cpython. Instead they rely on a JIT compiler. And it is syntax compatible but if your code uses any library or method relying on C extensions then you are out of luck (Goodbye NumPy.. etc).
Edit: They have C-layer emulation, but I don't know its limitations or current status, but you can use those libraries [1][2]
[1] https://www.pypy.org/posts/2018/09/inside-cpyext-why-emulati...