If you're not aware, check out evil-mode. https://github.com/emacs-evil/evil
While you enable it (usually by pressing Esc), Ctrl is "assumed" to be always pressed, so saving a file becomes "x s" (though when I am on Mac, I always map Cmd+S to save - and many other Cmd key based shortcuts that I used in every other app - thanks to emacs built-in shortcuts almost never using the Cmd key as it was designed for Unix).
It made using emacs much more enjoyable for me.
[1]: https://github.com/meow-edit/meow
[2]: https://esrh.me/posts/2021-12-18-switching-to-meow.html
Nvi has no syntax highlighting and is far less scriptable. Again, it's minimalist religion.
A lot of this is muscle memory.