I think pixel art looks awesome even in 2012. What do modern developers/artists think about its future, given that high-DPI displays may become the norm? Will there be 264 DPI pixel art?
I don’t think that drawing 1920x1080 (or larger!) images pixel-by-pixel will ever be practical, and it probably wouldn’t even look like pixel art to the eye at that point.
That said, once you switch over to more advanced scaling, the artist loses a lot of the fine control over the result that can really make pixel art shine.
(I would also like to play old adventure games like Full Throttle & Grim Fandango on the browser.)