>If my diet jacks up my leptin levels such that I don’t lose weight, that will show up on the scale, and I have to adjust my calories down to compensate.
>With this system I am guaranteed to lose weight so long as I don’t cheat.
Unfortunately, that's just not true. Here's some great quotes from the book "The Obesity Code" (which I've just recently found and find an excellent book):
>The abrupt increase in obesity began exactly with the officially sanctioned move toward a low-fat, high-carbohydrate diet.
>A 30 percent reduction in caloric intake results in a 30 percent decrease in caloric expenditure.
>Total energy expenditure is the sum of basal metabolic rate, thermogenic effect of food, nonexercise activity thermogenesis, excess post-exercise oxygen consumption and exercise.
>Since hormones control both Calories In and Calories Out, obesity is a hormonal, not a caloric, disorder.
>If hormones regulate fat growth, then obesity is a hormonal, not a caloric disorder.
>Sugar will increase the blood glucose level and provoke an insulin response from the pancreas. Olive oil will not...[cause] significant increase in blood glucose or insulin. The two different foods evoke vastly different metabolic and hormonal responses."
All of this is to say that it's not enough to simply adjust calories. Yes, calories matter to a point, and everyone knows that starvation (e.g., 0 calories for an extended period of time) is effective in the long-term, but starvation will also harm your body, and no reasonably-minded person can suggest it as a viable approach to weight loss.
The best available scientific evidence shows that continuing to decrease caloric intake can make weight loss more difficult for an obese person.