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They're generally airport codes, so Philadelphia and Amsterdam... unsure about FRE.

The IATA code FRE is assigned to Fera in the Solomon Islands. Freemont Airport does not have an IATA code.

Naming conventions can be inconsistent, and not every datacenter location has an airport. ASD is often used instead of AMS for Amsterdam.

ASD is the IATA code assigned to Andros Town Airport, in the Bahamas. It might also be a commonly used abbreviation for a medical condition.