-45C is something that would give pause to most ICE vehicles. Once you actually got it running sure it would be mostly fine and you could use the full range of the fuel onboard, but normal oil gets THICK at that temp, normal car batteries get pathetic, and your block will literally freeze (and crack open!) if you use common ICE antifreeze, which often only protects down to about -34F. Anything lower is a more specialized product.

Cars have had batteries in them that struggle at low temps for about a century. It's not something the average car user should be unfamiliar with.