I love your demo for this. It's one of the best demos I've ever come across in a launch HN. Very easy to understand and use. It seems to suffer with more complex questions though. For example:

Question: Why does the pUC19 plasmid have a high copy number in bacterial cells?

Expected answer: The pUC19 plasmid has a high copy number due to the lack of the rop gene and a single point mutation in the origin of replication (ori) derived from the plasmid pMB1.

GPT response: The pUC19 plasmid has a high copy number in bacterial cells due to the presence of the pUC origin of replication, which allows for efficient and rapid replication of the plasmid.

Both are technically correct - the expected answer is simply more detailed about the pUC origin, but both would be considered correct. It seems difficult to test things like this, but maybe that's just not possible to really get correct.

I wonder how well things like FutureHouse's wikicrow will work for summarizing knowledge better - https://www.futurehouse.org/wikicrow - and how that could be benchmarked against Talc